CAS · 11103-72-3
Product Overview
Ruthenium Red is a high-purity catalysts-auxiliary-agent supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Red-brown powder |
|---|---|
| Purity | 99.95% min |
| Ru content | 34.0% min |
| Pt | 0.005% max |
| Pd | 0.005% max |
| Rh | 0.003% max |
| Ir | 0.008% max |
| Au | 0.005% max |
| Ag | 0.0005% max |
| Cu | 0.0005% max |
| Fe | 0.0005% max |
| Ni | 0.0005% max |
| Al | 0.0005% max |
| Pb | 0.0003% max |
| Si | 0.01% max |
| Total Impurities | 0.05% max |
Applications
Ruthenium Red is primarily used in biochemical and pharmacological research as a selective inhibitor of calcium channels, particularly the ryanodine receptor and mitochondrial calcium uniporter. It is employed in studies investigating calcium signaling, intracellular calcium regulation, and mitochondrial function in various cell types and tissues. The compound is also used to probe the mechanisms of muscle contraction, neuronal signaling, and cellular responses to oxidative stress. In addition, Ruthenium Red serves as a staining agent in microscopy and histology for visualizing cellular structures rich in polysaccharides or calcium-binding proteins, aiding in tissue characterization and experimental imaging.
Benefits
Ruthenium Red offers several advantages in research and experimental applications. Its high specificity for certain calcium channels allows precise modulation of calcium-dependent pathways, making it a valuable tool for dissecting complex signaling mechanisms. The compound's strong binding affinity ensures consistent and reproducible inhibition in both in vitro and ex vivo studies. It also provides versatility in experimental design, functioning as both a pharmacological probe and a staining agent. Its ability to target mitochondrial and sarcoplasmic calcium channels supports the study of energy metabolism, muscle physiology, and neurobiology, making it particularly useful in detailed mechanistic investigations.
Conclusion
Ruthenium Red is a specialized research tool used in calcium signaling, mitochondrial studies, and histological staining. Its selective inhibition of calcium channels, reproducibility, and multifunctional applications make it valuable in cellular, tissue, and molecular research. Overall, Ruthenium Red supports the investigation of calcium-dependent processes, contributing to advances in physiology, pharmacology, and cellular biology.
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