CAS · 137330-13-3
Product Overview
Tilmicosin phosphate is a high-purity veterinary-medicine supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Grade | USP Grade |
|---|---|
| Description | Almost white or yellowish powder |
| Assay | 75% min |
| Tilmicosin Cis-isomers | 82.0% to 88.0% |
| Tilmicosin Trans-isomer | 12.0% to 18.0% |
Applications
1. Veterinary Medicine
Tilmicosin phosphate丨CAS 137330-13-3 is extensively used as a broad-spectrum veterinary antibiotic in livestock. Its applications include:
Treatment and prevention of respiratory diseases in:
Cattle (bovine respiratory disease, BRD)
Swine (porcine respiratory disease complex, PRDC)
Poultry (chronic respiratory disease)
Control of Mycoplasma, Pasteurella, and Actinobacillus spp.
Often administered orally via feed or water or subcutaneously in injectable forms.
2. Growth Promotion and Feed Efficiency (in some regions)
In certain regulatory environments, tilmicosin phosphate is used at subtherapeutic doses to promote growth performance and feed conversion efficiency in livestock.
This use is declining due to global efforts to limit antibiotic resistance development.
3. Pharmaceutical Formulation Development
Used in research and product development of:
Long-acting injectable formulations
Controlled-release feed additives
Water-soluble veterinary drug premixes
Its phosphate salt form enhances solubility and bioavailability, improving absorption in animal gastrointestinal tracts.
Benefits
1. Broad-Spectrum Antibacterial Activity
Active against Gram-positive bacteria, select Gram-negative pathogens, and Mycoplasma spp.
Effective in treating respiratory, systemic, and enteric infections in animals.
Exhibits bacteriostatic action by inhibiting protein synthesis through binding to the 50S ribosomal subunit.
2. Long Half-Life and Tissue Penetration
Tilmicosin accumulates in lung tissues and persists in respiratory tract secretions, providing extended duration of action.
Reduces the frequency of dosing and improves treatment compliance.
3. Low Cross-Resistance
Compared to older macrolides, tilmicosin phosphate often remains effective against resistant strains, although resistance management is critical.
4. Convenient Administration
Easily incorporated into feed, water, or injectable preparations.
Oral administration is particularly useful for mass medication in poultry and swine farming.
Conclusion
Tilmicosin phosphate丨CAS 137330-13-3 is a potent veterinary antibiotic known for its long-acting, broad-spectrum efficacy against major respiratory pathogens in livestock. It supports animal health, production efficiency, and disease control in intensive farming systems. While effective and widely used, responsible use aligned with antimicrobial stewardship guidelines is essential to preserve its efficacy and ensure food safety.
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