CAS · 328898-40-4
Product Overview
Tildipirosin is a high-purity veterinary-medicine supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White to light yellow crystalline powder |
|---|---|
| Assay (calculated on the anhydrous basis): | 98% min |
| Identification: | Meet the requirements |
| Solubility: | This product is easily soluble in methanol, ethanol or acetone and slightly soluble in water |
| Residue on ignition: | 0.1% max |
| Alkalinity: | 10-11 |
| Color of Ethanol Solution: | YG4 max |
| Related Compounds: | Should comply with regulation |
| Tildipirosin Isomer: | 2% max |
| Residual solvent: | 5000 ppm max |
| Bacterial Endotoxins: | 0.2 EU/mg max |
| Water: | 1% max |
| Heavy metals: | 20 ppm max |
Applications
1. Veterinary Medicine
Treatment of Bovine Respiratory Disease (BRD): Tildipirosin is widely used to control and treat respiratory infections in cattle caused by pathogens such as Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.
Swine Respiratory Disease: Effective against respiratory pathogens in pigs, including Actinobacillus pleuropneumoniae and Pasteurella multocida.
Poultry and Other Livestock: Occasionally used off-label for respiratory infections in other species under veterinary guidance.
2. Pharmacological Uses
Long-acting antibiotic: Due to its high tissue penetration and prolonged half-life, tildipirosin provides sustained therapeutic concentrations in lung tissues, allowing for less frequent dosing.
Parenteral administration: Delivered via injection or intramuscular route for rapid onset of action.
Benefits
1. Broad Spectrum Activity
Effective against a range of Gram-positive and Gram-negative bacteria commonly involved in respiratory diseases in livestock.
2. Improved Pharmacokinetics
Enhanced tissue penetration, especially in lung tissue, results in high bioavailability at the infection site.
Long half-life enables once-daily or single-dose treatment regimens, improving compliance and reducing stress in animals.
3. Reduced Resistance Potential
Structural modifications reduce susceptibility to common resistance mechanisms seen with other macrolides.
4. Safety Profile
Generally well-tolerated in target animals with a favorable safety margin when used according to veterinary guidelines.
5. Economic Benefits
By effectively controlling respiratory infections, tildipirosin helps reduce morbidity, mortality, and production losses in the livestock industry.
Conclusion
Tildipirosin (CAS 328898-40-4) is an advanced macrolide antibiotic widely used in veterinary medicine for the treatment and control of respiratory infections in cattle and swine. Its long-acting profile, broad antimicrobial spectrum, and targeted tissue delivery make it a valuable tool for improving animal health, welfare, and productivity in the livestock industry.
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