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Product Line: Pharmaceutical Chemicals

N-tert-Butylacrylamide

CAS 107-58-4

Molecular structure of N-tert-Butylacrylamide

CAS · 107-58-4

01

Product Overview

N-tert-Butylacrylamide is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance White fine crystals
Purity (by HPLC) 99% min
Color (Apha) 20 max
Melting point (°C) 127–130
Moisture (%) 0.5% max
Sulphate (mg/kg, ppm) 1000 max
Iron (ppm) 5 max
Turbidity (NTU) 1.0 max
03

Applications

N-tert-Butylacrylamide (CAS 107-58-4) is a versatile monomer widely used in the synthesis of specialty polymers and functional materials. It is primarily employed in the production of temperature- and pH-responsive polymers, such as poly(N-tert-butylacrylamide) and copolymers with acrylamide or other monomers, which are used in biomedical applications, drug delivery systems, and smart hydrogels. Its hydrophobic tert-butyl group provides tunable solubility and lower critical solution temperature (LCST) behavior, making it suitable for stimuli-responsive materials that swell or collapse in response to environmental changes. Additionally, it is used in coatings, adhesives, and surface modification, where it enhances hydrophobicity, chemical resistance, and thermal stability. N-tert-butylacrylamide is also applied in research and industrial polymerization studies to create functional copolymers and responsive networks for a variety of material science applications.

04

Benefits

The benefits of N-tert-butylacrylamide come from its chemical versatility, hydrophobic modification, and stability under polymerization conditions. The tert-butyl group provides steric hindrance that improves polymer thermal and mechanical stability while allowing tunable hydrophilicity in copolymers. Its reactivity in free radical and controlled/living polymerization techniques enables precise control over polymer composition, molecular weight, and architecture. The monomer's solubility in organic solvents and compatibility with other acrylamide-based monomers facilitates easy incorporation into copolymers, hydrogels, and functional materials. These characteristics allow the creation of polymers with predictable stimuli-responsive behavior, enhanced durability, and targeted performance for biomedical, industrial, and materials science applications.

05

Conclusion

N-tert-butylacrylamide is a valuable monomer for producing responsive and high-performance polymers in biomedical, industrial, and materials applications. Its hydrophobic tert-butyl group, chemical stability, and polymerization versatility enable precise control of polymer properties and stimuli-responsive behavior. By supporting the development of smart hydrogels, copolymers, and functional materials, N-tert-butylacrylamide remains a key building block in modern polymer and material science research.

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