CAS · 30414-53-0
Product Overview
Methyl 3-oxovalerate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Colorless or light yellow clear liquid |
|---|---|
| Identification | GC retention time similar to standard |
| Refractive Index | 1.420-1.425 |
| PH | 4.3-5.6 |
| Water | 0.20% max |
| Methyl Acetoacetate | 0.20% max |
| Ethyl 3-oxopentanoate | 0.1% max |
| Other single impurity | 0.20% max |
| Total impurities | 1.0% max |
| Assay | 99% min |
Applications
Methyl 3-oxovalerate (CAS 30414-53-0) is a versatile keto ester widely used as an intermediate in organic synthesis, pharmaceuticals, and fine chemicals. It serves as a key building block for the preparation of γ-lactones, substituted pyrroles, and other heterocyclic compounds. In medicinal chemistry, it is used to synthesize bioactive molecules, including enzyme inhibitors and pharmaceutical intermediates, where the keto and ester groups enable diverse transformations such as condensation, alkylation, and cyclization. Additionally, methyl 3-oxovalerate is utilized in the flavor and fragrance industry as a precursor for fruity and creamy aroma compounds, as well as in agrochemical synthesis for the development of herbicides and fungicides.
Benefits
The benefits of methyl 3-oxovalerate arise from its dual functional groups: a ketone and an ester. These groups provide high reactivity, allowing for selective modifications in complex synthetic pathways. The compound's moderate volatility and good solubility in organic solvents facilitate handling and incorporation into multi-step reactions. Its chemical stability under standard storage conditions ensures reliability in industrial and laboratory applications. Additionally, the keto ester functionality enables efficient derivatization, supporting structural diversification, optimization of bioactivity, and the generation of intermediates with tailored physicochemical properties.
Conclusion
Methyl 3-oxovalerate is a highly versatile intermediate that plays a critical role in organic synthesis, pharmaceuticals, and flavor chemistry. Its combination of ketone and ester functionalities allows for selective, efficient transformations, making it a valuable tool for producing heterocycles, bioactive molecules, and aroma compounds. By providing synthetic flexibility, stability, and reactivity, methyl 3-oxovalerate continues to be an essential building block in modern chemical and pharmaceutical development.
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