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Product Line: Pharmaceutical Chemicals

Methyl 2-chloroisobutyrate

CAS 22421-97-2

Molecular structure of Methyl 2-chloroisobutyrate

CAS · 22421-97-2

01

Product Overview

Methyl 2-chloroisobutyrate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance: Light yellow or yellow liquid
Purity: 98% min
03

Applications

Methyl 2-chloroisobutyrate is a versatile halogenated ester widely used as an intermediate in pharmaceutical, agrochemical, and fine chemical synthesis. Its reactive chloro group and ester functionality enable a variety of chemical transformations, including nucleophilic substitution, amidation, and transesterification, making it suitable for the preparation of carboxylic acid derivatives, amides, and heterocyclic compounds. In medicinal chemistry, it serves as a building block for the synthesis of enzyme inhibitors, antiviral agents, and other bioactive molecules. It is also employed in agrochemical research to produce herbicides and pesticides, as well as in organic synthesis for the development of specialty chemicals and functionalized intermediates.

04

Benefits

The benefits of methyl 2-chloroisobutyrate stem from its chemical reactivity, stability, and versatility. The chloro substituent provides a reactive site for selective nucleophilic substitution reactions, allowing efficient introduction of functional groups. The ester group enables easy derivatization into acids, amides, or other esters, facilitating multi-step synthesis. Its high purity and well-defined structure ensure reproducible reactions and high yields in laboratory and industrial applications. Additionally, the compound's small molecular size and solubility in organic solvents make it convenient for handling, storage, and incorporation into synthetic pathways.

05

Conclusion

Methyl 2-chloroisobutyrate is a highly valuable halogenated ester intermediate for pharmaceutical, agrochemical, and fine chemical synthesis. Its combination of chloro and ester functionalities provides versatile reactivity and efficient derivatization opportunities, supporting the production of bioactive molecules, heterocycles, and functionalized intermediates. By enabling selective and reproducible chemical transformations, it remains an essential building block in organic synthesis and industrial chemical development.

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