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Product Line: Pharmaceutical Chemicals

Methyl 2,4-dichloropyrimidine-5-carboxylate

CAS 3177-20-6

Molecular structure of Methyl 2,4-dichloropyrimidine-5-carboxylate

CAS · 3177-20-6

01

Product Overview

Methyl 2,4-dichloropyrimidine-5-carboxylate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance: Light yellow solid
Purity (HPLC): 97% min
Identification: HNMR
Total impurities: 3.0% max
Single impurity: 2.0% max
Water: 0.5% max
03

Applications

Methyl 2,4-dichloropyrimidine-5-carboxylate is an important halogenated pyrimidine derivative widely used as a versatile intermediate in pharmaceutical, agrochemical, and fine chemical synthesis. It serves as a valuable building block for the preparation of various biologically active compounds, including antiviral agents, anticancer drugs, herbicides, and fungicides. The electron-deficient pyrimidine ring, combined with reactive chloro substituents, makes it highly suitable for nucleophilic substitution reactions and heterocyclic modifications. It is also employed in the synthesis of kinase inhibitors and other pyrimidine-based drug scaffolds.

04

Benefits

The compound offers excellent chemical reactivity due to the presence of two chlorine atoms and an ester functional group, enabling diverse substitution and condensation reactions under mild conditions. Its structure allows for straightforward functionalization at multiple positions, providing flexibility for complex molecule design. Methyl 2,4-dichloropyrimidine-5-carboxylate demonstrates good stability, high purity, and compatibility with a wide range of organic solvents, making it reliable for both research and industrial-scale synthesis.

05

Conclusion

Methyl 2,4-dichloropyrimidine-5-carboxylate is a highly valuable intermediate in the synthesis of pyrimidine-based pharmaceuticals and agrochemicals. Its dual chlorine functionality and ester moiety provide synthetic versatility, enabling the efficient development of advanced heterocyclic compounds with diverse biological activities.

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