CAS · 50-57-7
Product Overview
Lypressin is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White powder |
|---|---|
| Purity (HPLC) | 98% |
| Acetate Content (HPLC) | 12.0% max |
| Peptide Content (N%) | 80.0% min |
| Water Content (Karl Fischer) | 10.0% max |
| MS (ESI) | Confirms |
| Mass Balance | 95% ~ 105% |
| Sequence | H-[Cys-Tyr-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2 |
| Storage | Cool and dry place (2–8℃, away from light) |
Applications
Lypressin is a synthetic peptide hormone and an analog of vasopressin used primarily in the medical field. It is employed for its antidiuretic and vasoconstrictive properties in the treatment of diabetes insipidus, a condition characterized by excessive urination and thirst due to insufficient endogenous vasopressin. Additionally, lypressin is used in controlling bleeding in certain surgical procedures, particularly in patients with hemophilia or uremic bleeding, due to its ability to promote vasoconstriction and enhance platelet aggregation. It also finds application in research settings for studying water balance, kidney function, and vasopressin receptor activity, making it a valuable tool in endocrinology and pharmacology studies.
Benefits
The primary benefits of lypressin stem from its high specificity and potency as a vasopressin analog. It effectively mimics natural antidiuretic hormone activity, providing reliable control of water retention and urine output in patients with diabetes insipidus. Its ability to induce vasoconstriction at targeted sites helps manage bleeding during surgical procedures, enhancing patient safety and outcomes. Lypressin is relatively stable and can be formulated for parenteral or intranasal administration, allowing flexible therapeutic use. Furthermore, its predictable pharmacological profile and reduced side-effect potential compared to natural vasopressin make it a safer and more convenient option for clinical and research applications.
Conclusion
Lypressin is a valuable synthetic peptide with critical applications in the management of diabetes insipidus and bleeding disorders, as well as in pharmacological research on vasopressin activity. Its specificity, potency, and stability make it a reliable therapeutic and research tool, enabling precise regulation of water balance, vascular function, and platelet activity. By combining efficacy with versatility in administration, lypressin plays an essential role in both clinical treatment and scientific investigation.
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