L-Phenylalanine, (alphaS)-alpha-((2-(4-morpholinyl)acetyl)amino)benzenebutanoyl-L-leucyl-
CAS 868540-16-3
CAS · 868540-16-3
Product Overview
L-Phenylalanine, (alphaS)-alpha-((2-(4-morpholinyl)acetyl)amino)benzenebutanoyl-L-leucyl- is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White to off white solid |
|---|---|
| Purity | 99% min |
| AB005-10-BY-3 | 0.1% max |
| AB005-10-BY-2 | 0.3% max |
| AB005-9 | 0.3% max |
| Unknown single impurity | 0.15% max |
| Total impurities | 1% max |
| Water content (KF) | 1% max |
Applications
L-Phenylalanine, (alphaS)-alpha-((2-(4-morpholinyl)acetyl)amino)benzenebutanoyl-L-leucyl- (CAS 868540-16-3) is a specialized peptide derivative used primarily in pharmaceutical and biochemical research. This compound serves as an intermediate in the synthesis of protease inhibitors, enzyme modulators, and other bioactive peptides. Its structure, which includes L-phenylalanine, L-leucine, and a morpholinylacetyl moiety, provides both stereochemical specificity and functional versatility, making it suitable for incorporation into larger peptide chains or peptidomimetics. It is utilized in drug discovery programs targeting proteases, metabolic enzymes, and receptor systems, and is valuable for studying structure–activity relationships (SAR) in peptide-based therapeutics.
Benefits
The benefits of this compound lie in its stereochemical purity, functional diversity, and peptide-mimicking properties. The (alphaS)-configuration ensures correct three-dimensional alignment, which is essential for biological activity and receptor binding. The morpholinylacetyl group enhances solubility, bioavailability, and metabolic stability, while the combination of L-phenylalanine and L-leucine provides a hydrophobic core that can improve interaction with protein targets. Its well-defined chemical structure allows for selective derivatization and incorporation into complex synthetic sequences, facilitating the development of potent and selective therapeutic candidates. Additionally, its stability and compatibility with standard peptide synthesis methodologies make it a practical intermediate for laboratory and industrial applications.
Conclusion
L-Phenylalanine, (alphaS)-alpha-((2-(4-morpholinyl)acetyl)amino)benzenebutanoyl-L-leucyl- is a valuable peptide intermediate for pharmaceutical research and drug development. Its stereochemical integrity, functional versatility, and chemical stability make it ideal for synthesizing bioactive peptides and peptidomimetics. By enabling precise design and optimization of enzyme inhibitors and other therapeutic molecules, this compound plays a key role in modern medicinal chemistry and peptide-based drug discovery.
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