CAS · 80-41-1
Product Overview
Ethanol, 2-chloro-, 1-(4-methylbenzenesulfonate) is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Colorless or light yellow liquid |
|---|---|
| Purity (GC) | 95.0% min |
| Water content | 0.5% max |
Applications
Ethanol, 2-chloro-, 1-(4-methylbenzenesulfonate) is primarily used as a reactive intermediate in organic synthesis. Its structure, featuring a tosylate (4-methylbenzenesulfonate) leaving group and a chloro-substituted ethanol moiety, enables it to participate in nucleophilic substitution and etherification reactions. The compound is employed in the preparation of complex alcohol derivatives, ethers, and halogenated compounds in pharmaceutical, fine chemical, and agrochemical synthesis. In research laboratories, it is used to study reaction mechanisms involving tosylate activation, haloalcohol transformations, and multi-step functionalization processes. Its versatility also makes it suitable for constructing intermediates for biologically active molecules and for developing synthetic methodologies that require selective reactivity at the alcohol position.
Benefits
The compound offers several advantages due to its reactive tosylate group and chloro functionality. The tosylate provides an excellent leaving group, allowing efficient nucleophilic displacement reactions under mild conditions. Its dual functionality enables sequential transformations, including halogen substitution and ether formation, making it a flexible intermediate for multi-step synthesis. The compound is stable under standard storage conditions, ensuring reproducible reactions and predictable outcomes. Additionally, it is compatible with a range of organic solvents and reaction conditions, facilitating smooth incorporation into laboratory and industrial-scale synthetic workflows. These properties make it a practical and reliable building block for complex molecule construction.
Conclusion
Ethanol, 2-chloro-, 1-(4-methylbenzenesulfonate) is a versatile intermediate used in the synthesis of alcohol derivatives, ethers, and halogenated compounds. Its applications in organic synthesis, combined with benefits such as reactivity, stability, and versatility, make it an important tool in pharmaceutical, fine chemical, and research chemistry. The compound supports efficient, high-yield synthesis of complex molecules and enables the development of diverse functionalized intermediates.
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