CAS · 36082-50-5
Product Overview
5-Bromo-2,4-dichloropyrimidine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Colorless to yellowish liquid |
|---|---|
| Purity (GC): | 99.0% min |
| Moisture: | 0.5% max |
| Maximum single impurity: | 0.5% max |
| Identification (GC): | Retention time of major peak in the chromatogram of the sample solution should correspond to that of standard solution as obtained in the assay |
Applications
1. Pharmaceutical Intermediate
Serves as a building block for the synthesis of various pyrimidine-based drugs, including antiviral, anticancer, and antimicrobial agents.
Its halogen substituents facilitate further functionalization through nucleophilic aromatic substitution or cross-coupling reactions.
2. Agrochemical Synthesis
Utilized in the preparation of herbicides, fungicides, and insecticides containing pyrimidine scaffolds.
Acts as a key intermediate enabling selective modifications for potency and selectivity.
3. Organic Synthesis
Employed in cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to introduce diverse functional groups on the pyrimidine ring.
Useful for constructing complex heterocyclic compounds in research and industrial applications.
4. Material Science
Used in the development of functional materials and ligands due to its reactive halogenated structure.
Benefits
✔️ High Reactivity
The presence of electron-withdrawing halogen atoms at the 2,4, and 5 positions enhances reactivity for substitution and coupling reactions, facilitating efficient synthesis pathways.
✔️ Versatile Functionalization
Allows selective replacement of halogens with nucleophiles, enabling diverse chemical modifications.
✔️ Key Intermediate
Widely accepted as a valuable precursor for producing biologically active heterocycles.
Conclusion
5-Bromo-2,4-dichloropyrimidine is a valuable halogenated pyrimidine intermediate extensively used in pharmaceutical and agrochemical syntheses. Its reactive halogen atoms allow for diverse chemical transformations, making it essential for developing new bioactive molecules and materials.
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