5-amino-2,4-ditert-butylphenol

5-amino-2,4-ditert-butylphenol is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

5-Amino-2,4-di-tert-butylphenol is a highly functionalized phenolic compound commonly used as an intermediate in the synthesis of antioxidants, UV stabilizers, and pharmaceutical agents. In polymer and coating industries, it serves as a building block for sterically hindered phenolic antioxidants (BHT derivatives), which protect plastics, rubbers, and resins from oxidative degradation and thermal aging. Its amino and phenolic groups allow further chemical modification to produce stabilizers, corrosion inhibitors, and UV absorbers for coatings, adhesives, and lubricants. In pharmaceutical research, it is utilized as a precursor for bioactive molecules and heterocyclic compounds, particularly those requiring electron-rich aromatic systems with steric protection. Additionally, it finds applications in fine chemical synthesis, where its sterically hindered structure enhances selectivity and stability in organic transformations.

The benefits of 5-amino-2,4-di-tert-butylphenol stem from its sterically hindered phenol and reactive amino functionalities. The bulky tert-butyl groups provide steric protection, reducing undesired side reactions and enhancing antioxidant efficiency. The phenolic hydroxyl offers radical scavenging activity, while the amino group allows further derivatization or cross-linking in polymer systems, enabling multifunctional applications. Its chemical and thermal stability ensures consistent performance under high-temperature or oxidative conditions. The compound's solubility and compatibility with various organic solvents and resins improve processing and incorporation into formulations. By combining structural rigidity, reactivity, and steric hindrance, it enhances product longevity, prevents discoloration, and maintains mechanical integrity in industrial applications.

5-Amino-2,4-di-tert-butylphenol (CAS 873055-58-4) is a versatile intermediate for antioxidants, UV stabilizers, and pharmaceutical synthesis. Its sterically hindered phenolic and amino functionalities provide high chemical stability, reactivity, and efficiency in radical scavenging and polymer protection. By supporting durable, high-performance materials and enabling selective chemical transformations, it plays a key role in industrial formulations, materials stabilization, and advanced organic synthesis.

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