CAS · 504-17-6
Product Overview
4,6-Dihydroxy-2-mercaptopyrimidine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Yellowish powder |
|---|---|
| Assay | 99% min |
| Loss on drying | 0.50% max |
| Sulphated ash | 0.50% max |
| Dimer | 0.20% max |
Applications
4,6-Dihydroxy-2-mercaptopyrimidine (CAS 504-17-6) is a multifunctional heterocyclic compound widely used in pharmaceuticals, biochemical research, and coordination chemistry. It serves as a building block for the synthesis of antiviral, antimicrobial, and anticancer agents, as well as other biologically active pyrimidine derivatives. Its hydroxyl and thiol groups enable selective chemical modifications, including alkylation, acylation, and condensation reactions, facilitating the preparation of diverse substituted pyrimidines. Additionally, it is employed as a chelating ligand in metal complex formation, useful for catalysts, sensors, and analytical reagents. The compound is also applied in structure–activity relationship studies, enabling researchers to explore functional modifications on the pyrimidine scaffold.
Benefits
The benefits of 4,6-dihydroxy-2-mercaptopyrimidine come from its dual nucleophilic sites (hydroxyl and thiol groups), heterocyclic stability, and versatility in derivatization. Its rigid pyrimidine ring ensures structural stability, while the thiol and hydroxyl functionalities allow selective and efficient chemical transformations. The compound is compatible with standard organic and inorganic reaction conditions, providing reproducible and high-yielding reactions. These properties make it a valuable intermediate for synthesizing biologically active compounds, functional metal complexes, and chemical probes, supporting both research and industrial applications.
Conclusion
4,6-Dihydroxy-2-mercaptopyrimidine is a versatile heterocyclic intermediate used in pharmaceuticals, biochemical research, and coordination chemistry. Its hydroxyl and thiol functionalities combined with the stable pyrimidine core enable efficient derivatization and functionalization. By facilitating the synthesis of bioactive molecules and metal complexes, it remains an important building block in medicinal chemistry and advanced chemical research.
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