CAS · 13159-28-9
Product Overview
3beta-Hydroxy-Lup-20(30)-en-28-al is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White powder |
|---|---|
| Purity | 98% min |
| Solubility | Soluble in methanol |
| Identification | UV spectrum by HPLC-DAD ¹H NMR spectroscopy |
Applications
3β-Hydroxy-Lup-20(30)-en-28-al (CAS 13159-28-9) is a lupane-type triterpenoid aldehyde widely used in natural product chemistry, medicinal chemistry, and pharmaceutical research. It serves as a key intermediate for the synthesis and structural modification of bioactive triterpenoids, including derivatives explored for anticancer, anti-inflammatory, antiviral, and antimicrobial activities. The presence of both a hydroxyl group and an aldehyde functionality enables selective oxidation, reduction, and condensation reactions, allowing the preparation of a broad range of functional analogues. It is also used in structure–activity relationship studies to investigate how modifications on the lupane skeleton influence biological activity, making it valuable in drug discovery and natural product-based research.
Benefits
The benefits of 3β-hydroxy-lup-20(30)-en-28-al arise from its rigid pentacyclic structure, multifunctional reactivity, and defined stereochemistry. The lupane backbone provides structural stability and a hydrophobic framework that is favorable for biological interactions. The β-oriented hydroxyl group and aldehyde moiety offer versatile sites for chemical derivatization, enabling fine control over polarity, reactivity, and biological performance of derivatives. Its well-defined configuration supports reproducible synthesis and consistent biological evaluation. These features make it an efficient and adaptable scaffold for developing triterpenoid-based compounds with enhanced activity and selectivity.
Conclusion
3β-Hydroxy-Lup-20(30)-en-28-al is a valuable triterpenoid intermediate used in medicinal chemistry and natural product research. Its multifunctional structure and stable lupane framework enable diverse chemical transformations and systematic biological optimization. By supporting the development of novel bioactive derivatives and advancing triterpenoid-based drug research, it remains an important building block in pharmaceutical and chemical science.
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