CAS · 27246-81-7
Product Overview
3-Bromophenylhydrazine hydrochloride is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Item | Specification |
|---|---|
| Appearance | White or slight yellow powder |
| Purity | 98% min (HPLC) |
| Moisture | 0.5% max |
Applications
1. Organic Synthesis
a. Hydrazone Formation
● 3-Bromophenylhydrazine hydrochloride丨CAS 27246-81-7 is often used as a reactive intermediate in the synthesis of hydrazone derivatives. Hydrazones are important intermediates in the synthesis of various pharmaceutical and biologically active compounds.
● Typically, it reacts with carbonyl compounds (aldehydes and ketones) to form hydrazones, which are crucial in designing compounds for further biological testing or applications in medicinal chemistry.
b. Synthesis of Hydrazine Derivatives
● Used in the preparation of aromatic hydrazines or hydrazine-based heterocycles, which can be further utilized in the development of pharmaceuticals or agrochemicals.
c. Coupling Reactions
● As a brominated aromatic hydrazine, it is an excellent candidate for cross-coupling reactions, such as Suzuki-Miyaura or Sonogashira coupling, to form more complex molecules.
● It may also be involved in the synthesis of substituted phenyl compounds and aromatic amines used in various industries.
2. Pharmaceutical Applications
a. Precursor for Pharmaceutical Compounds
● 3-Bromophenylhydrazine hydrochloride is utilized as a precursor in the synthesis of potential drug candidates, especially in the development of antifungal, antibacterial, and antiviral agents.
● It plays a role in the modification of known drug molecules, offering opportunities for SAR (Structure-Activity Relationship) studies to design more efficient therapies.
b. Anticancer and Antimicrobial Properties
● Some derivatives synthesized from 3-Bromophenylhydrazine have been evaluated for their potential as anticancer or antimicrobial agents, acting on specific cellular pathways.
3. Agrochemical Applications
● Pesticide Development: 3-Bromophenylhydrazine hydrochloride丨CAS 27246-81-7 is occasionally used in the synthesis of agrochemicals, particularly in the development of pesticides, fungicides, and herbicides.
● The compound can be modified to form various bioactive agents that target plant diseases or pests, providing a valuable tool in crop protection.
4. Material Science and Polymer Chemistry
a. Polymerization Reactions
● In material science, 3-Bromophenylhydrazine hydrochloride is utilized in the polymerization of certain hydrazine-based monomers for the production of specialty polymers or coatings. Its reactivity helps to crosslink polymer chains and modify polymer properties.
b. Functionalized Polymers
● As part of polymer chemistry, it may be used to introduce functional groups into polymers, creating materials with enhanced properties for use in coatings, adhesives, or films.
Benefits
√ High Reactivity
● The presence of the bromine atom at the 3-position on the phenyl ring makes this compound a highly reactive intermediate, facilitating efficient coupling reactions, substitution, and hydrazone formation.
√ Versatile Reagent
● 3-Bromophenylhydrazine hydrochloride can be used in a wide variety of synthetic reactions, making it a versatile reagent in organic chemistry and the development of complex molecules.
√ Pharmaceutical Relevance
● With its role as a precursor to bioactive compounds, this compound is valuable for the pharmaceutical industry, particularly in the development of drugs with potential antimicrobial or anticancer properties.
√ Cross-Coupling Reactions
● The bromine atom makes it an excellent candidate for cross-coupling reactions such as Suzuki, Sonogashira, and others, which are commonly used in the synthesis of complex organic molecules.
√ Effective in Polymer Chemistry
● 3-Bromophenylhydrazine hydrochloride can be used in polymer chemistry to produce functionalized polymers with enhanced properties for various industrial applications.
Conclusion
3-Bromophenylhydrazine hydrochloride丨CAS 27246-81-7 is a versatile intermediate in organic synthesis, with a broad range of applications across pharmaceuticals, agrochemicals, materials science, and polymer chemistry. Its ability to undergo cross-coupling reactions, as well as its utility in the synthesis of hydrazone derivatives and bioactive compounds, makes it an invaluable reagent in synthetic chemistry.
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Conclusion
A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.