CAS · 502496-36-8
Product Overview
3-Bromo-5-fluoro-2-methylaniline is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Light brown solid |
|---|---|
| Purity: | 98% min |
Applications
1. Pharmaceutical Intermediate
Due to its functional groups, this compound is frequently used as an intermediate in the synthesis of pharmaceuticals. The halogen atoms (bromine and fluorine) allow for further modifications via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), aiding in the production of drug candidates with desired biological activity.
2. Agrochemical Development
It serves as a building block in the development of agrochemicals such as herbicides, insecticides, or fungicides. The electron-withdrawing halogens and electron-donating methyl group on the aromatic ring contribute to tailored activity profiles.
3. Fine Chemicals and Specialty Compounds
Useful in synthesizing dyes, pigments, and specialty aromatic compounds where precise substitution on the benzene ring is required. It provides an excellent starting point for creating structurally diverse and functionally active molecules.
4. Research and Development
Widely used in chemical and medicinal research for structure-activity relationship (SAR) studies. Its substituted aniline framework allows researchers to explore how electronic and steric effects impact molecular interactions in target systems.
Benefits
Versatile Reactivity: The presence of bromine and fluorine allows for site-specific functionalization through well-established organic reactions.
Electron Modulation: The combination of halogens and a methyl group enables fine-tuning of electronic properties of the aromatic ring, valuable for drug design.
Synthetic Utility: Acts as a robust starting material or intermediate for various chemical transformations.
Structural Rigidness: Aromatic substitution provides a stable core structure for further derivatization.
Conclusion
3-Bromo-5-fluoro-2-methylaniline is a highly functionalized aromatic amine that plays an important role in chemical synthesis, particularly in the pharmaceutical and agrochemical industries. Its halogen substitutions and reactivity make it a powerful intermediate for creating structurally complex and biologically active compounds. As synthetic and medicinal chemistry continues to evolve, such intermediates remain critical tools for innovation and product development.
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