CAS · 1780644-81-6
Product Overview
3-Bromo-5-(tert-butyl)benzobthiophene is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Light yellow liquid |
|---|---|
| Assay | 98% min |
Applications
3-Bromo-5-(tert-butyl)benzothiophene (CAS 1780644-81-6) is an important heteroaromatic intermediate used in pharmaceuticals, materials science, and advanced organic synthesis. In drug discovery, it serves as a building block for bioactive molecules, especially in oncology and anti-inflammatory research, where benzothiophene scaffolds are valued for their pharmacological properties. In material science, it is used in the design of organic semiconductors, light-emitting materials, and photovoltaic components due to the electronic properties of the benzothiophene ring. The bromine substituent makes it a suitable candidate for cross-coupling reactions (Suzuki, Stille, Negishi), enabling the creation of functionalized derivatives for both medicinal chemistry and functional materials.
Benefits
The benefits of 3-bromo-5-(tert-butyl)benzothiophene lie in its structural versatility, reactivity, and stability. The bromine atom provides a reactive handle for a wide range of coupling reactions, while the tert-butyl group improves solubility, steric control, and lipophilicity, which are advantageous in drug design and material applications. The benzothiophene core contributes aromatic stability, electron-rich character, and strong interactions with biological targets or electronic systems. These features make the compound a highly adaptable intermediate for tailoring molecules with enhanced pharmacological activity or advanced optoelectronic performance.
Conclusion
In summary, 3-bromo-5-(tert-butyl)benzothiophene is a versatile synthetic intermediate with applications in pharmaceuticals, organic electronics, and functional materials. Its utility comes from its reactive bromine substituent, steric and solubility advantages of the tert-butyl group, and the stable, electronically favorable benzothiophene scaffold. These combined properties make it a valuable building block for developing both innovative medicines and high-performance materials.
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