CAS · 156-06-9
Product Overview
2-Oxo-3-phenylpropanoic acid is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Faint yellow solid |
|---|---|
| Purity (HPLC) | 95.0% min |
| 1H-NMR Identification | Conform to structure |
| Loss on Drying | 1.0% max |
Applications
2-Oxo-3-phenylpropanoic acid (CAS 156-06-9), also known as phenylpyruvic acid, is an α-keto acid widely used as an intermediate in pharmaceutical, biochemical, and fine chemical synthesis. In pharmaceuticals, it serves as a precursor for the synthesis of amino acids, peptides, and enzyme inhibitors. It is also used in the production of chiral compounds, where its keto and carboxyl functional groups allow selective derivatization for asymmetric synthesis. In biochemical research, 2-oxo-3-phenylpropanoic acid is employed as a substrate in enzymatic assays, particularly for studying transaminases and other oxidative enzymes. Additionally, it is used in organic synthesis for constructing heterocycles, phenyl-substituted derivatives, and fine chemicals for research and industrial applications.
Benefits
The benefits of 2-oxo-3-phenylpropanoic acid stem from its dual functional groups-the keto and carboxyl moieties-which provide versatile reactivity for chemical transformations. The keto group allows condensation, reduction, and amination reactions, while the carboxylic acid can undergo esterification, amidation, and salt formation. Its phenyl substitution imparts stability and hydrophobic character, enhancing selectivity in synthetic applications. These features make it a highly adaptable intermediate for constructing complex molecules, enabling efficient and selective synthesis in pharmaceuticals, biochemical studies, and fine chemical research.
Conclusion
In summary, 2-oxo-3-phenylpropanoic acid is a valuable α-keto acid used in pharmaceuticals, biochemical assays, and organic synthesis. Its applications include amino acid synthesis, enzyme substrate studies, and heterocycle construction, while its benefits lie in versatile reactivity, functional group compatibility, and structural stability. As a multifunctional intermediate, it remains an important tool for advancing research and development in both medicinal and chemical industries.
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