CAS · 61717-82-6
Product Overview
2-Iodoxybenzoic acid is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White to light yellow solid or powder |
|---|---|
| Assay (2-Iodoxybenzoic acid) (w/w,%): | 44%–49% |
| Stabilizer - Benzoic Acid (w/w,%): | 22%–23% |
| Stabilizer - Isophthalic Acid (w/w,%): | 29%–33% |
Applications
2-Iodoxybenzoic acid (IBX) (CAS 61717-82-6) is a hypervalent iodine reagent widely used in organic synthesis as a selective oxidizing agent. It is primarily employed for the oxidation of alcohols to carbonyl compounds, including primary alcohols to aldehydes and secondary alcohols to ketones, under mild conditions. IBX is also utilized in oxidative transformations of heterocycles, oxidative cleavage reactions, and in the synthesis of complex natural products and pharmaceuticals. Its compatibility with various solvents and substrates makes it a versatile tool for both laboratory-scale and industrial organic synthesis.
Benefits
The benefits of 2-iodoxybenzoic acid stem from its high selectivity, mild reaction conditions, and environmental friendliness compared to traditional heavy metal oxidants. It provides efficient oxidation without over-oxidation or degradation of sensitive functional groups, which is particularly important in multi-step synthesis. IBX is relatively stable, easy to handle, and allows for precise control over reaction outcomes. Its organic, non-metallic nature reduces toxic byproducts, supporting greener synthetic practices in academic and industrial chemistry.
Conclusion
2-Iodoxybenzoic acid is a highly effective and selective oxidizing agent with broad applications in organic synthesis. Its mild and controlled oxidation capabilities, stability, and environmentally friendly profile make it valuable for the preparation of aldehydes, ketones, and other oxidized intermediates. By enabling efficient and selective transformations, IBX remains an important reagent in pharmaceutical, natural product, and fine chemical synthesis.
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