2-(2,2-difluorobenzod1,3dioxol-5-yl)acetonitrile
CAS 68119-31-3
CAS · 68119-31-3
Product Overview
2-(2,2-difluorobenzod1,3dioxol-5-yl)acetonitrile is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Colorless to yellowish liquid |
|---|---|
| Identification (GC) | Retention time of major peak in the chromatogram of the sample solution should correspond to that of standard solution as obtained in the assay |
| Moisture | 0.5% max |
| Purity (GC) | 98% min |
| Maximum single impurity | 1% max |
| Solvent residue | 0.5% max |
Applications
2-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)acetonitrile is primarily used as an intermediate in the development of pharmaceuticals, agrochemicals, and fine chemicals. Its difluorinated benzodioxole core provides a valuable structural motif for designing bioactive molecules with enhanced metabolic stability and improved binding affinity. The nitrile group allows further chemical transformations such as amination, reduction, or hydrolysis, making the compound adaptable for constructing diverse functional derivatives. It is commonly employed in medicinal chemistry programs aimed at producing enzyme inhibitors, receptor ligands, and small-molecule modulators. In agrochemical synthesis, it contributes to the formation of herbicides, fungicides, and insecticides where fluorinated aromatic components enhance activity and environmental persistence.
Benefits
The benefits of this compound lie in its combination of a difluorinated aromatic ring and a reactive nitrile functionality. The difluorobenzodioxole moiety contributes to improved lipophilicity, metabolic resistance, and increased molecular rigidity, which can elevate the effectiveness of lead compounds in drug or pesticide development. The nitrile group provides synthetic versatility, enabling chemists to construct a wide range of final molecules with precise functional and structural attributes. Its chemical stability supports handling in multi-step syntheses, while the compact structure allows efficient incorporation into frameworks designed to optimize potency and selectivity. These features make it a practical and high-value building block for advanced molecular design.
Conclusion
2-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)acetonitrile is a valuable intermediate used in pharmaceutical, agrochemical, and fine chemical synthesis. Its fluorinated aromatic structure enhances stability and biological potential, while the nitrile group enables diverse downstream transformations. Together, these properties make the compound an effective building block for creating high-performance bioactive molecules and supporting innovation in modern chemical research and product development.
Previous
N-Aminoethylpiperazine丨CAS 140-31-8
Next