CAS · 73367-80-3
Product Overview
12-Bromododecanoic acid is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Off-white or white solid |
|---|---|
| Purity: | 97% min |
| Loss on drying: | 1.0% max |
Applications
1. Organic Synthesis Intermediate
12-Bromododecanoic acid is widely used as a building block or intermediate in organic synthesis:
Enables nucleophilic substitution reactions via the bromine atom.
Useful for introducing long alkyl chains in chemical synthesis.
Precursor for making amide, ester, and thioester derivatives.
2. Polymer and Surfactant Development
Its amphiphilic nature (hydrophobic tail and polar acid head) makes it valuable in the design of surfactants, emulsifiers, and specialty polymers.
Often modified into functionalized fatty acids or esters to enhance compatibility with synthetic polymers or coatings.
3. Lipid and Membrane Research
Serves as a model compound in lipid research due to its long aliphatic chain.
Studied for its interaction with biomembranes and its behavior in micelle or bilayer formation.
4. Synthesis of Functionalized Materials
Used in preparing self-assembled monolayers (SAMs) and functionalized surfaces by attaching the carboxyl end to solid supports, leaving the alkyl or reactive end exposed for further modification.
5. Medicinal Chemistry and Drug Delivery
Acts as a lipophilic linker or tail in prodrug design, allowing drug molecules to anchor in lipid membranes or enhance bioavailability.
6. Nanomaterial Surface Modification
Applied in surface grafting or tailoring nanostructure properties (e.g., quantum dots, nanoparticles) due to the reactivity of both ends (Br and COOH groups).
Benefits
✅ Dual Reactivity
The bromine atom enables further substitution with nucleophiles (e.g., amines, thiols), while the carboxylic acid allows for esterification, amide formation, or salt formation.
✅ Versatility
Can be converted into a wide range of derivatives, enabling applications in various industries-from pharma to materials science.
✅ Hydrophobic Tail
The long alkyl chain offers strong hydrophobic interaction, useful in surfactant chemistry, lipid delivery systems, or biointerface design.
✅ Stability and Handleability
As a saturated fatty acid derivative, it is relatively stable under ambient conditions, making it easier to handle and store than more reactive intermediates.
✅ Customizable Functional Groups
Easily modified to tailor physical or chemical properties of molecules or materials for targeted applications.
Conclusion
12-Bromododecanoic acid (CAS 73367-80-3) is a valuable intermediate in organic, materials, and pharmaceutical chemistry. Its combination of a reactive bromine and a functional acid group, along with a hydrophobic tail, makes it ideal for chemical derivatization, surface modification, and amphiphilic molecule design. Whether in lipid science, drug delivery, or advanced materials, it offers a versatile platform for innovation.
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