CAS · 16495-13-9
Product Overview
(S)-(+)-Benzyl glycidyl ether is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Colorless to pale yellow liquid |
|---|---|
| Chemical Purity (GC) | 99% min |
| Enantiomeric Excess (HPLC) | 99% min |
| Specific Rotation (c=5 in toluene) [α]20D | +4.7° to +6.7° |
| Water | 0.5% max |
Applications
(S)-(+)-Benzyl glycidyl ether is a chiral epoxide widely used as an intermediate in pharmaceutical synthesis, asymmetric synthesis, and material chemistry. It serves as a key building block for the preparation of enantiomerically pure compounds, including chiral alcohols, amino alcohols, and other bioactive molecules. In medicinal chemistry, it is employed in the synthesis of drugs, enzyme inhibitors, and chiral ligands for asymmetric catalysis. Additionally, (S)-(+)-benzyl glycidyl ether is utilized in the production of epoxy resins, polymer modifiers, and specialty coatings, where its epoxide group allows for crosslinking and functionalization of polymeric materials. Its stereochemistry is particularly valuable in applications requiring high enantiomeric purity to ensure biological activity or catalytic selectivity.
Benefits
The benefits of (S)-(+)-benzyl glycidyl ether are derived from its chiral nature, high reactivity, and versatility. Its epoxide functionality enables selective ring-opening reactions, allowing efficient formation of diverse chiral intermediates. The (S)-configuration provides enantiomeric control, which is crucial for producing biologically active molecules with predictable pharmacological properties. Its stability and solubility in organic solvents facilitate handling and integration into multi-step syntheses. Additionally, it supports the preparation of functionalized polymers and resins, contributing to enhanced material properties such as flexibility, adhesion, and chemical resistance. These characteristics make it a valuable intermediate for both pharmaceutical development and materials science applications.
Conclusion
In summary, (S)-(+)-benzyl glycidyl ether is a chiral epoxide with applications in pharmaceutical synthesis, asymmetric catalysis, and polymer chemistry. Its benefits include enantiomeric purity, high reactivity, stereochemical control, and versatility in forming bioactive molecules and functionalized materials. By combining chemical functionality with chiral precision, (S)-(+)-benzyl glycidyl ether remains an important compound for advanced organic synthesis and materials development.
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